Insidermedicine Daily News (Video)
Insidermedicine is a physician-led news organization that allows you to keep on top of the latest evidence-based medical information by w...Science & Medicine
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23:00:00 02/09/12
Scientists Reverse Alzheimer's Disease in a Mouse Model; Children Exposed to Chemo in Womb Develop Normally; Effects of Malaria on Fetal Growth (Video)
[LESS INFO] 2 VIEWS | ADDED 23:00:00 02/09/12
(February 9, 2012 - Insidermedicine)
From Cleveland - A drug has been shown to reverse symptoms of Alzheimer's disease in a mouse model, according to a report published in Science . Researchers found that Bexarotene given to mice with Alzheimer's disease quickly cleared amyloid plaques in the brain and reversed the rodents cognitive defects.
From Belgium - Children who are exposed to chemotherapy in the womb still develop normally, according to a report published in the Lancet Oncology. Researchers studied 68 pregnancies of cancer patients, during which 236 cycles of chemotherapy were administered. Results of cognitive, heart and health assessments during long term follow-up revealed that the children developed as well as children in the general population.
And finally, from Thailand - Research published in PLoS ONE identifies how malaria effects fetal growth. Using ultrasound to study nearly 3,800 pregnancies, researchers found that fetal head size was significantly smaller when the mother was infected with malaria.
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23:00:00 02/08/12
Heart Disease May Be Passed From Father to Son; Depressed Children More Likely to Be Bullied; Fasting May Improve Cancer Treatment (Video)
[LESS INFO] 4 VIEWS | ADDED 23:00:00 02/08/12
(February 8, 2012 - Insidermedicine)
From the UK - Coronary artery disease may be passed genetically from father to son, according to a report published in the Lancet. Researchers studied blood samples from over 3,000 men, finding that men who carried a particular Y chromosome mutation had a 50% increased risk of the common heart disease.
From Arizona - Depressed adolescents are more likely to be bullied, according to a report published in Child Development . Studying nearly 5,000 children in grades 4-6, researchers found that those who exhibited symptoms of depression in grade 4 were more likely to be victimized by their peers in grade 5 and have difficulty with peer acceptance in grade 6.
And finally, from California - A new report published in Science Translational Medicine finds that fasting may improve cancer treatment. Researchers found that multiple fasting cycles used in conjunction with chemotherapy cured 20% of mice with an aggressive form of childhood cancer and 40% of mice with a more limited form of the disease.
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21:00:00 02/07/12
Parkinson's Disease Origins Discovered; Metabolic Profile Essential to Tailoring Cancer Therapy; Finger Foods During Weaning May Help Prevent Childhood Obesity (Video)
[LESS INFO] 4 VIEWS | ADDED 21:00:00 02/07/12
(February 7, 2012 - Insidermedicine)
From Buffalo - Scientists have discovered the origins of Parkinson's disease, according to a report published in Nature Communications . Researchers studied live human neurons of two Parkinson's disease patients, finding that mutations to their parkin gene prevented dopamine from supporting neural computation and resulted in the death of dopamine neurons. Injecting the neurons with a normal parkin gene, the researchers were able to reverse these defects.
From San Francisco - A new report published in Cell Metabolism finds that metabolic profiles are fundamental to personalizing cancer treatment. Studying mice with different cancer causing genes, researchers found that the rodents tumours had very different metabolisms--emphasizing that need for metabolic profiling when planning cancer therapy.
And finally, from the UK - Weaning infants on finger foods as opposed to spoon fed purees may help prevent obesity, according to a report published in BMJ Open . Resaerchers followed 155 children from 20 months old to 6.5 years old, finding that those who were allowed to feed themselves with finger foods during weaning were more likely to prefer healthy foods and less likely to be overweight or obese than those who ate spoon fed-purees.
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21:50:00 02/06/12
Smoking Causes Rapid Mental Decline in Men; 3 Cancer Drugs Found to Raise Risk of Death; Positive Behavior Reinforcement May Reduce Bullying, Peer Rejection (Video)
[LESS INFO] 4 VIEWS | ADDED 21:50:00 02/06/12
(February 6, 2012 - Insidermedicine)
From London - Smoking causes rapid mental decline in men, according to a report published in the Archives of General Psychiatry. Researchers studied over 7,000 men and women for 25 years, finding that men who smoked had more rapid cognitive decline than women and non-smokers, and that those who smoked during the entire followup period demonstrated greater decline in all cognitive tests.
From Boston - 3 cancer drugs may raise risk of fatal side effects, although this risk is still very low, according to a report published in the Journal of Clinical Oncology . Results of a meta-analysis covering over 4600 cancer patients found that treatment with either sorafenib, sunitinib, or pazopanib resulted in 1.5% of patients having fatal complications, compared with 0.7% of patients given standard therapy or placebo.
And finally, from Baltimore - A behavioural prevention model can reduce bullying and peer rejection in schools, according to a report published in the Archives of Pediatric and Adolescent Medicine . Studying over 12,000 children, researchers found that the School-wide Positive Behavioral Interventions and Supports model as an alternative to zero-tolerance policies greatly reduced teacher-reported bullying and peer-rejection.
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21:00:00 02/01/12
Diabetes Video: New Medicine for Type 1 Diabetes Fails in Trials; Surgical Breast Biopsy Numbers Skewed; Eating Fish While Pregnant May Boost Cognitive Development in Child
[LESS INFO] 14 VIEWS | ADDED 21:00:00 02/01/12
(February 1, 2012 - Insidermedicine)
From Sweden - A developmental medicine for type 1 diabetes has failed to show significant effects in a phase 3 trial published in the New England Journal of Medicine . Researchers randomized over 300 patients recently diagnosed with type 1 diabetes to either 4 doses of the novel medicine, 2 doses of the medicine plus placebo or 4 doses of placebo. Results showed some positive changes to C-peptide levels, but no significant effects.
From Philadelphia - According to a report published in the Journal of the American College of Radiology , surgical breast biopsies are not being overused. Researchers found that 30% of breast biopsies were classified as surgical, when in fact the amount of true surgical biopsies was somewhere between 2 and 18%.
And finally, from Spain - Eating fish while pregnant may improve cognitive development in the child, according to a report published in the American Journal of Clinical Nutrition . Researchers collected blood samples from 2,000 women at 20 weeks gestation and from the infant's umbilical cord. They found that women who consumed the most fish during pregnancy had children that scored higher in verbal intelligence and fine motor skills tests and demonstrated increased prosocial behaviour.
14 Views
23:00:00 01/31/12
Heart Failure Linked to Mental Decline; Exercise Improves Health, Quality of Life in Cancer Patients; New Drug May Improve Survival in Advanced Prostate Cancer Patients (Video)
[LESS INFO] 14 VIEWS | ADDED 23:00:00 01/31/12
(January 31, 2012 - Insidermedicine)
From Australia - A new report published in the European Heart Journal finds that heart failure may cause mental decline. Researchers used MRI scans to study the brains of 35 heart failure patients, 56 heart disease patients and 64 healthy controls. Imaging revealed that the heart failure patients had worse memory than controls, and also reduced grey matter in brain regions associated with cognitive and emotional activity.
From Hong Kong - Exercise can improve health in cancer patients, according to a report published in the BMJ. Results of a meta-analysis examining over 30 trials found that exercise benefited cancer patients by improving their BMI and blood sugar control, reducing depression and greatly enhancing quality of life.
And finally, from Maryland - A novel drug may improve survival in advanced prostate cancer patients, according to a report presented at the American Society of Clinical Oncology meeting. Researchers randomized men with drug-resistant prostate cancer to treatment with the drug MDV3100 or placebo. They found that the novel drug improved survival in the patients, resulting in a 37% reduced risk of death.
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16 Views
22:30:00 01/30/12
Milk May Boost Brain Function; Difference in Blood Pressure Between Arms May Predict Heart Disease, Death; Family Doctors in UK Experiencing High Burnout Rates (Video)
[LESS INFO] 16 VIEWS | ADDED 22:30:00 01/30/12
(January 30, 2012 - Insidermedicine)
From Maine - A daily glass of milk may boost memory and brain function, according to a report published in the International Dairy Journal . Researchers studied nearly 1,000 men and women ages 23 to 98, administering a series of tests that measure visual-spatial, verbal and working memory ability. Results showed that individuals who drank the most milk scored the highest on the tests--while milk drinkers were 5x less likely to fail the tests than non-milk drinkers.
From the UK - Checking blood pressure in both arms may help detect heart disease, according to a report published in the Lancet. Results of a meta-analysis found that a difference of 15mm Hg in systolic blood pressure between arms raised risk of heart disease and mortality.
And finally, from the UK - Family doctors in the UK have high levels of burnout, according to a report published in BMJ Open. Researchers surveyed over 550 general practitioners , finding that 46% said they were emotionally exhausted, 42% were depersonalized and 34% felt like they were not achieving anything
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21:00:00 01/29/12
Anaphylaxis After Vaccine Very Rare; Working 11 Hour Days May Cause Depression; Many Smokers Do Not Quit, Even After Lung Cancer Diagnosis (Week in Review)
[LESS INFO] 13 VIEWS | ADDED 21:00:00 01/29/12
(January 29, 2012 - Insidermedicine)
From the UK - Anaphylactic shock following vaccination is an extremely rare event, according to a report published in the Archives of Disease in Childhood . From 2008-2009, researchers noted only 7 confirmed cases of anaphylaxis following vaccination among over 5.5 million children vaccinated.
From London - A new report published in PLoS ONE finds that people who work too much are at raised risk of depression. Studying 2000 civil servants, researchers found that individuals who worked 11 or more hours a day had a twofold increased risk of suffering a major depressive episode.
And finally, from Boston - Research published in CANCER finds that many patients continue to smoke even after being diagnosed with cancer. Examining nearly 5,500 colorectal and lung cancer patients, researchers found that a substantial minority of these patients continued smoking 5 months after their diagnosis.
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21:00:00 01/28/12
Elderly at Raised Risk of Infection Following ER Visit; Brain Activities May Ward off Alzheimer's Disease; Oral HPV Infection More Common in Men than Women (Week in Review)
[LESS INFO] 14 VIEWS | ADDED 21:00:00 01/28/12
(January 28, 2012 - Insidermedicine)
From Montreal - The elderly are at significantly increased risk of infection following a visit to the emergency department, according to a report published in CMAJ . Studying over 1200 elderly residents of long term care facilities, researchers found that individuals were at 3x increased risk of a new respiratory or GI infection in the week following an emergency department visit.
From California - Keeping your brain active may reduce risk of Alzheimer's disease, according to a report published in the Archives of Neurology. Researchers studied 65 healthy elderly patients, as well as 10 Alzheimer disease patients and 11 young controls. They found that individuals who participated in more brain stimulating activities throughout their life, particularly in their early and middle years, had reduced levels of %beta-amyloid protein--a major component of AD development.
And finally, from Ohio - A new report presented at the Multidisciplinary Head and Neck Cancer Symposium finds that HPV-related cancers are more common in men than women. Studying over 5,500 adult men and women, researchers found that oral HPV infections were 3x more common in men than women, and that men were 5x more likely to have an HPV 16 infection--a form of the virus that raises risk of head and neck cancer by 14x
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22:30:00 01/26/12
Lung Cancer Video: New Test May Be Able to Predict Lung Cancer Death; 40% of Rheumatoid Arthritis Patients Are Inactive; HPV-Related Cancers More Common in Men than Women
[LESS INFO] 15 VIEWS | ADDED 22:30:00 01/26/12
(January 26, 2012 - Insidermedicine)
From California - A new test may accurately predict risk of dying from lung cancer, according to a report published in the Lancet. Researchers used a novel molecular assay to blindly examine 433 patients with early stage lung cancer, as well as over 1000 lung cancer patients in China. They found the assay was accurate in predicting who was at low, intermediate or high risk of dying from the disease 5 years following lung cancer surgery.
From Chicago - Over 40% of rheumatoid arthritis patients are physically inactive, according to a report published in Arthritis Care & Research . Studying nearly 200 RA patients, researchers found that 2 in 5 reported participating in no physical activity, while 53% said they lacked motivation for physical activity and 49% did not believe that physical activity would have any benefits.
And finally, from Ohio - A new report presented at the Multidisciplinary Head and Neck Cancer Symposium finds that HPV-related cancers are more common in men than women. Studying over 5,500 adult men and women, researchers found that oral HPV infections were 3x more common in men than women, and that men were 5x more likely to have an HPV 16 infection--a form of the virus that raises risk of head and neck cancer by 14x
16 Views
22:30:00 01/25/12
Heart Attack Deaths Halved in Past 10 Years; Working Too Much Linked to Depression; 10 Year Heart Attack Risk Prediction Can Give False Sense of Security (Video)
[LESS INFO] 16 VIEWS | ADDED 22:30:00 01/25/12
(January 25, 2012 - Insidermedicine)
From Oxford- Heart attack death rates in England have been dramatically reduced in the last 10 years, according to a report published in the BMJ . Studying over 860,000 heart attacks from 2002-2010, researchers noted a 50% decline in heart attack deaths among men and a 53% decline among women.
From London - A new report published in PLoS ONE finds that people who work too much are at raised risk of depression. Studying 2000 civil servants, researchers found that individuals who worked 11 or more hours a day had a twofold increased risk of suffering a major depressive episode.
And finally, from Chicago - Doctors may be giving patients a false sense of security regarding their heart attack risk, according to a report published in the NEJM . In a study of over 250,000 people, researchers reviewed the effectiveness of providing patients with a prediction of their 10 year risk for heart attack. They found that the short-term risk prediction is misleading and provides patients with a false sense of security, since having just one risk factor for heart attack, such as high blood pressure or cholesterol, greatly increases one's lifetime risk of heart attack.
13 Views
21:00:00 01/24/12
Anaphylactic Shock After Vaccination Extremely Rare; Elderly at 3x Raised Risk of Infection Following ER Visit; New Target for Deadly Brain Cancer (Video)
[LESS INFO] 13 VIEWS | ADDED 21:00:00 01/24/12
(January 24, 2012 - Insidermedicine)
From the UK - Anaphylactic shock following vaccination is an extremely rare event, according to a report published in the Archives of Disease in Childhood . From 2008-2009, researchers noted only 7 confirmed cases of anaphylaxis following vaccination among over 5.5 million children vaccinated.
From Montreal - The elderly are at significantly increased risk of infection following a visit to the emergency department, according to a report published in CMAJ. Studying over 1200 elderly residents of long term care facilities, researchers found that individuals were at 3x increased risk of a new respiratory or GI infection in the week following an emergency department visit.
And finally, from Atlanta - Research published in Cancer Discovery finds a possible new pathway that may improve treatment of lethal brain cancer. Scientists used glioblastoma samples and cancer stem cells, finding a novel pathway that allowed treatment to overcome resistance of the brain tumour.
14 Views
21:00:00 01/23/12
Alzheimer's Disease Video: Keeping Brain Active May Reduce Risk of Alzheimer's Disease; Targeting One Protein May Fight Several Cancers; Many Smokers Don't Quit After Cancer Diagnosis
[LESS INFO] 14 VIEWS | ADDED 21:00:00 01/23/12
(January 23, 2012 - Insidermedicine)
From California - Keeping your brain active may reduce risk of Alzheimer's disease, according to a report published in the Archives of Neurology. Researchers studied 65 healthy elderly patients, as well as 10 Alzheimer disease patients and 11 young controls. They found that individuals who participated in more brain stimulating activities throughout their life, particularly in their early and middle years, had reduced levels of %beta-amyloid protein--a major component of AD development.
From Germany - Two reports published in the Journal of Experimental Medicine find a single protein that may be key to fighting several forms of cancer. In the first study, researchers found that inhibiting the protein HSP90 slowed breast tumour growth in a mouse model, while the second study revealed that HSP90 inhibitors also slowed the growth of leukaemia cells in a mouse model.
And finally, from Boston - Research published in CANCER finds that many patients continue to smoke even after being diagnosed with cancer. Examining nearly 5,500 colorectal and lung cancer patients, researchers found that a substantial minority of these patients continued smoking 5 months after their diagnosis.
14 Views
21:00:00 01/22/12
Statins May Have Cancer Fighting Ability; 1 in 10 Canadians Unable to Afford Medications; Melanoma Death Rates Drop, But Only Among Most Educated (Week in Review)
[LESS INFO] 14 VIEWS | ADDED 21:00:00 01/22/12
(January 22, 2012 - Insidermedicine)
From New York - Statins may have cancer fighting ability, according to a report published in Cell . Scientists examined cancer cells in an artificial model of the human breast, finding that mutations in the tumour suppressing gene p53 led to disorganized and invasive growth of the cancer cells. When the p53 mutation was treated with statins, researchers saw the cancer cells stop their invasive growth and even die.
From British Columbia - 10% of Canadians cannot afford prescription drugs, according to a report published in the CMAJ . Researchers surveyed nearly 6,000 Canadians, finding that 1 in 10 participants reported not taking prescription drugs as directed due to cost.
From Georgia - Melanoma death rates are dropping, but only among those with the most education, according to a report published in the Archives of Dermatology . Studying death certificates from 26 American states, researchers found that melanoma death rates dropped by 10% from 1997 to 2007. The researchers noted, however, that these rates declined only in individuals who had at least 13 years of education.
14 Views
21:00:00 01/21/12
Obesity Rates in the US Remain Unchanged; Cigarette Smoke Causes Emphysema; Insomnia Linked to Many Serious Health Problems (Week in Review)
[LESS INFO] 14 VIEWS | ADDED 21:00:00 01/21/12
(January 21, 2012 - Insidermedicine)
From Maryland - Obesity rates in the US are still high and have not changed much in recent years, according to a report published in JAMA . Analyzing data from a nationally representative sample, researchers found that one in three adults and one in six children and teens are obese, while there have been increases in obesity rates among certain demographics.
From Texas - A new report published in Science Translational Medicine describes how cigarette smoke causes emphysema. Studying mice, researchers found that toxic cigarette smoke activates a host of genes in the immune system that in turn inflame the lungs, resulting in emphysema.
And finally, from Quebec - A new report published in the Lancet emphasizes the importance of diagnosing and treating insomnia early. Researchers reviewed evidence regarding the sleep disorder, finding that insomnia patients are over 5x more likely to have anxiety and depression, 2x more likely to develop congestive heart failure and diabetes, and 7x more likely to develop substance abuse problems
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21:00:00 01/20/12
PCE in Drinking Water Linked to Bipolar Disorder, PTSD; Neurodegeneration May Be Cause by Genetic Mutation; Exercise Eases Anxiety in Women (Video)
[LESS INFO] 15 VIEWS | ADDED 21:00:00 01/20/12
(January 20, 2012 - Insidermedicine)
From Boston - PCE in the drinking water significantly raises risk of mental illness, according to a report published in Environmental Health . Researchers followed children born between 1969 n 1983--a time in which water pipes were known to be leaking PCE, a chemical used to dry-clean clothes, into drinking water supply. They found that prenatal and early childhood exposure to the solvent resulted in a 2x increased risk of bipolar disorder and 50% increased risk of PTSD.
From Maine - A new report published in Cell identifies a possible cause of neurodegeneration. Researchers noted a mutation in 1 copy of the U2 snRNA gene that caused neurodegeneration in a mouse model.
And finally, from Georgia - Exercise helps ease anxiety in women, according to a report published in Psychotherapy and Psychosomatics. Researchers assigned 30 sedentary women suffering from generalized anxiety disorder to either an aerobic exercise group or a control group. They found that the exercise group experienced significant reductions in their worry symptoms, as well as moderate reductions in their irritability, tension and pain.
03/10/09